Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case Report
Published: May 1, 2020 | DOI: https://doi.org/10.7860/JCDR/2020/44269.13724
Aroop Mohanty, Suneeta Meena, Uttam Kumar Nath, Sudeep Vaniyath, Neelam Kaistha
1. Assistant Professor, Department of Microbiology, AIIMS Rishikesh, Uttarakhand, India.
2. Assistant Professor, Department of Laboratory Medicine, AIIMS, New Delhi, India.
3. Additional Professor, Department of Medical Oncology and Haematology, AIIMS Rishikesh, Uttarakhand, India.
4. Senior Resident, Department of Medical Oncology and Haematology, AIIMS Rishikesh, Uttarakhand, India.
5. Professor, Department of Microbiology, AIIMS Rishikesh, Uttarakhand, India.
Correspondence
Dr. Aroop Mohanty,
Assistant Professor, Department of Microbiology, AIIMS Rishikesh, Veerbhadra Marg, Rishikesh-249203, Uttarakhand, India.
E-mail: aroopmohanty7785@yahoo.com
Although Candida albicans remains the predominant species causing Blood Stream Infection (BSI), recent studies have demonstrated an emergence of Non-albicans Candida spp (NAC), such as C. glabrata, C. papapsilosis and C. krusei. Candida krusei are yeast-like microorganisms which may colonise the human skin, respiratory or gastrointestinal tract but can cause lethal infections especially in immunocompromised patients. Hereby, author’s report a case of 10-year-old male with T-cell Acute Lymphocytic Leukaemia (ALL) who reported with fever and non-productive cough caused by Candida krusei. Direct gram stain from blood culture and germ tube test was performed. Further, the isolate was initially misidentified by Matrix Assisted Laser Desorption/Ionisation Time of Flight Mass Spectrometry (MALDI-TOF MS) as Trichosporon ovoides which was later identified by molecular sequencing as Candida krusei.
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